Best time of day to take Mounjaro? When is the best time to take Mounjaro? How often do you take Mounjaro? After -67lbs of Mounjaro weight loss, I’ll share what has worked best for me on my tirzepatide weight loss journey!
This post is about best time of day to take Mounjaro.
Weight Loss Encouragement Emails:
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Updated: January 24, 2025 // Published: October 17, 2023 // Written by: Elizabeth Skordinski
Best Time Of Day To Take Mounjaro?

I am not a doctor, nor pretend to play one on the internet. Always talk with your own medical professional.
Mounjaro is injectable prescription medicine and is GLP-1 receptor agonists by the manufacturer Eli Lilly.
I have lost -67lbs on Mounjaro and have been on Mounjaro for almost 41 weeks (so far!).
I usually feel Mounjaro starting 12 hours after I take my Mounjaro injection.
| HARDEST DAY EXAMPLES: | SOLUTION DAY EXAMPLES: | HALF LIFE DAYS: | WHAT DAY IS BEST FOR YOU? |
| FRI EVENING | I TAKE ON THURS 3-4PM | WED & THURS | |
| SAT EVENING | I TAKE ON FRI 3-4PM | THURS & FRI | |
| TUES AFTERNOON | I TAKE MONDAY EARLY AFTERNOON | SUN & MON |
Reverse Engineer for you when should you take Mounjaro. This will be different for everyone.
My shot has given me Mounjaro fatigue and also Mounjaro constipation as some of my side effects. The best way I have combated the constipation and fatigue is with magnesium at night (for sure the day before my shot, day of shot and day after my shot). Side effects also effect the best time for my shot.
You will need to first start by knowing How often do you take Mounjaro?
How often do you take Mounjaro?
Moujaro is taken once a week with a single-dose pen as an injectable medication.
With taking every 7 days, you will want to think backwards when taking your first shot.
Injection of Mounjaro is subcutaneously:
- Upper Arm
- Upper thigh
- Abdomen
Best Time Of The Day To Take Mounjaro?
Tip 1: Look at your schedule. Do you have family commitments, work commitments or personal commitments that are important to you? Yes? You will factor this in for taking your first shot and that same day of the week for weeks ahead.

Tip 2: Look at your schedule. Do you have any important lunch, dinner, party or food central events? Yes? You can factor this into your first shot date.
Ideally, you share with important people that you may not be as hungry and feel free to indulge without you engaging in old habits. And more so for first time taking Mounjaro 2.5mg.
This gives friends and/or family permission to not change their habits. And allows you to stay focused on your new habits without feeling guilt. (No guilt, shame or condemenation here friends!)
Tip 3: When do you usually have foods challenges? The weekend?

When is the best time to take Mounjaro?
Click to access COUNTESS-OF-SHOPPING-REVERSE-ENGINEER-SHOT-DAY.pdf

Friends, this is what has worked for me.
I want to encourage you to find out what works best for you when taking your Mounjaro pens.
Always talk to your doctor about changing from seven days to less or more days for your Mounjaro injection.
Learning new lifestyle changes with food and physical activity will help on your treatment plan.

And also as I increase the dose of Mounjaro, my times may change:
- Mounjaro 2.5mg (Starting dose and lowest dose)
- Mounjaro 5 mg
- Mounjaro 7.5mg
- Mounjaro 10mg
- Mounjaro 12.5mg
- Mounjaro 15mg (Highest dose)
This does not mean I won’t get Mounjaro side effects with that particular dose as I titrate up.
Read about 3 Best Mounjaro Injection Sites.

(For Mounjaro side effect solutions, READ MORE HERE.)
Possible Side Effects Of Mounjaro
As you titrate up doses of Mounjaro, you may experience different side effects & possible symptoms.
Possible side effects & the most common side effects of Mounjaro can include:
- Nausea
- Diarrhea
- Nausea
- Vomiting
- Constipation
- Indigestion
- Stomach Pain
- Sulfur burps or burping
- Acid reflux
- Hair loss
- Loose skin
- Body Aches
- Mounjaro Face
- Mounjaro Butt
- Tired
- Sleep changes
- Period Changes
Mounjaro Severe Side Effects
Always talk with your medical healthcare professional about serious side effects. Seek immediate medical attention & get medical help for:
- Severe vomiting
- Symptoms of gallbladder problems (there are several, but severe pain in the upper right abdomen)
- Severe belly pain that may spread to your back or chest as this could inflammation of the pancreas
- Severe stomach pain
- Severe gastroparesis
- Risk of thyroid cancer (this boxed warning is in relation to a particular type of thyroid cancer has had family history of thyroid cancer & thyroid tumors for information at the writing of this article. )
- Abdominal pain
- Severe stomach problems
Symptoms Of Pancreatitis Are (Per Johns Hopkins Medicine):
- Severe belly pain that may spread to your back or chest (it may feel worse after you eat)
- Nausea.
- Vomiting.
- Rapid heart rate.
- Fever.
- Swelling and feeling sore or tender in your upper belly.
- Fluid buildup in your belly.
- Lowered blood pressure.
Do not wait if you are having symptoms of a serious allergic reaction.
Talk to your medical provider about missed dose of prescription medicines. Also talk to your healthcare provider about birth control pills & the type of birth control due to emptying of your stomach can potentially effect.

Join FREE Mounjaro, Wegovy & Ozempic Encouragement Group [HERE]

Mounjaro Injection Shopping
Read more about Mounjaro 2.5 mg weight loss when you are just starting HERE.
How long can Mounjaro stay out of the fridge (READ HERE)?


Best Overall: LMNT ELECTROLYTES
“Massively has helped with when I get Mounjaro side effects like diarrhea, leg cramps, headaches, constipation as I titrate up. Has no sugar or junk ingredients…just potassium, magnesium and sodium. If it’s too salty, simply dilute.”
Most Popular: 40 Ounce Stanley Quencher H2.0 FlowState Stainless Steel Tumbler
“My Stanley helps me drank SO MUCH MORE WATER on Mounjaro! I’m also super clumsy and w/ the spill lock, I don’t spill my water bottle. LOVE LOVE LOVE!”
Most Helpful: Loose Skin Cream
“The loose skin cream has dramatically helped me on my Mounjaro weight loss journey. It is NOT a miracle worker, but DOES help me visibly see results with my loose skin.”
Weight Loss Measurement: Smart Tape Measure That Syncs
“When I’ve had Mounjaro weight loss stalls, this is what gets me through it.”
Most Used: Meal Plan
“With Mounjaro weight loss, I needed an easy meal plan that fit with taking injections. This meal plan has been beyond exciting on my Mounjaro weight loss journey!”
Sharps Container – You will need somewhere to dispose of your Mounjaro, Wegovy or Ozempic syringe after injecting it. I love this container, but it’s smaller to fight underneath your bathroom sink, but large enough to fit the Mounjaro injection afterwards. SHOP HERE Biohazard Needle & Syringe Disposal

Alcohol Prep Pads
Alcohol Prep Pads For Injection Site – I didn’t realize prior to my Mounjaro injections that I should make sure my injection site was clean with an alcohol pads. I love these because they are so little I can easily store them with my other Mounjaro items. SHOP HERE.

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Need Mounjaro Lunch Ideas? Here are some Mounjaro lunch and dinner ideas that are working well for me.






